If you want to covert your single-program PocketPCR device into an open-ended and reprogrammable
thermocycler capable of storing multiple flexibly-defined cycling programs and being controlled and
reprogrammed from a controller PC with a graphical interface, then download the PocketPCRController
Arduino code and
PocketPCR_Programmable C# WPF solution from github
In some computers running Windows 10, the BioEdit Setup.exe file (created with an old version
of InstallShield Express) may generate a virus alert in Windows Defender, even though Windows
Defender will not detect a virus if the file is scanned directly. If this happens, testing suggests
that the installer executing in memory will still complete and BioEdit will install OK, even
though Windows Defender will automatically remove Setup.exe from the disk.
If this is an issue or is concerning to you, the full package of files required for running BioEdit
is packaged in BioEditFullFolder.zip without an installer program. The full contents of BioEditFullFolder.zip
can simply be unzipped to a single folder and BioEdit.exe can be run from that folder. Before unzipping or running
Bioedit.exe, however, it is advisable to do a virus scan with whatever scanner you trust.
Also, checking the MD5 or SHA1 checksum is not a bad idea for the security conscious.
SHA1 checksum for BioEditFullFolder.zip: 688d6607f0ace12f93a92019788f07231e2aef1c
MD5 checksum: for BioEditFullFolder.zip: a2abd9b2373905dd4bd1fc610f62e3ee
SHA1 checksum for BioEdit.zip: 464122273e30a9c2e418ae8b109d1db9933f4ff4
MD5 checksum: for BioEdit.zip: 434aae3df9243a74700536b6a23744dd
The checksum of a file can be generated in a Windows command shell with the CertUtil command:
CertUtil -hashfile MD5 (for MD5), or
CertUtil -hashfile (for SHA1)
Note: BioEdit is no longer
being regularly maintained, and the documentation is out of date and no
longer maintained. BioEdit is
free for use by any and all interested parties,
but is supplied as is. Users must agree with the
terms of the license.
Note also that the web site that BioEdit was hosted on for many years (www.mbio.ncsu.edu)
no loger exists (nor does the RNase P database), as Dr. James Brown has retired, the Microbiology
department at NCSU has been reorganized, and the mbio.ncsu.edu server no longer exists. For this
reason, the ancient "BioEdit" web site has been minimally migrated to a Github Pages site to allow
people to continue to download the program if they still find it useful.